SCHEMBL21586835

SCHEMBL21586835

O=C(Nc1ccc(F)cc1F)c1cc(NC(=O)[C@@H]2C(c3ccc(F)c(Cl)c3)C2(Cl)Cl)ccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
LMNA P02545 3/20 0.49
TAS1R3 Q7RTX0 1/20 0.44
TAS1R1 Q7RTX1 1/20 0.44
TAS1R2 Q8TE23 1/20 0.44
ALDH1A1 P00352 2/20 0.40
RECQL P46063 1/20 0.40
GRM4 Q14833 1/20 0.40
MAPT P10636 4/20 0.39
MAPK1 P28482 2/20 0.39
HDAC1 Q13547 1/20 0.38
FADS1 O60427 1/20 0.38
KDM4E B2RXH2 1/20 0.37
KLK7 P49862 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18147311 1.00 MEN1 (0.49) MEN1KMT2ALMNATAS1R3TAS1R1
SCHEMBL18147308 1.00 MEN1 (0.49) MEN1KMT2ALMNATAS1R3TAS1R1
SCHEMBL18147305 1.00 MEN1 (0.49) MEN1KMT2ALMNATAS1R3TAS1R1
SCHEMBL18146403 0.95 KMT2A (0.47) MEN1KMT2ALMNATAS1R3TAS1R1
SCHEMBL21022021 0.95 KMT2A (0.47) MEN1KMT2ALMNATAS1R3TAS1R1
SCHEMBL18146032 0.95 KMT2A (0.47) MEN1KMT2ALMNATAS1R3TAS1R1
SCHEMBL21021286 0.95 KMT2A (0.47) MEN1KMT2ALMNATAS1R3TAS1R1
SCHEMBL18146400 0.95 KMT2A (0.47) MEN1KMT2ALMNATAS1R3TAS1R1
SCHEMBL18147232 0.94 KMT2A (0.49) MEN1KMT2ALMNATAS1R3TAS1R1
SCHEMBL20051171 0.94 KMT2A (0.49) MEN1KMT2ALMNATAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3578543-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow AgroSciences LLC (US) 2019-12-11 EP disclosed