SCHEMBL21587217

SCHEMBL21587217

c1ccc(-c2ccc(N(c3ccccc3)c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3cc(N(c5ccccc5)c5ccccc5)ccc3-4)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PDK2 Q15119 3/20 0.36
TDP2 O95551 1/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
OPRK1 P41145 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
ATM Q13315 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13137305 1.00 MAPT (0.36) MAPTL3MBTL1KDM4EALDH1A1CYP1A2
SCHEMBL13137309 0.98 MAPT (0.35) MAPTL3MBTL1KDM4EALDH1A1CYP1A2
SCHEMBL13137320 0.98 MAPT (0.35) MAPTL3MBTL1KDM4EALDH1A1CYP1A2
SCHEMBL13137298 0.98 PDK2 (0.36) MAPTL3MBTL1KDM4EALDH1A1CYP1A2
SCHEMBL17461746 0.97 PDK2 (0.40) MAPTL3MBTL1KDM4EALDH1A1CYP1A2
SCHEMBL13937778 0.97 MAPT (0.36) MAPTL3MBTL1KDM4EALDH1A1CYP1A2
SCHEMBL13137335 0.97 MAPT (0.36) MAPTL3MBTL1KDM4EALDH1A1CYP1A2
SCHEMBL13937781 0.97 MAPT (0.36) MAPTL3MBTL1KDM4EALDH1A1CYP1A2
SCHEMBL13937779 0.97 MAPT (0.36) MAPTL3MBTL1KDM4EALDH1A1CYP1A2
SCHEMBL13937791 0.97 MAPT (0.36) MAPTL3MBTL1KDM4EALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11864460-B2 Organic light emitting device LG CHEM, LTD. (KR) 2024-01-02 US disclosed
US-11864460-B2 Organic light emitting device LG CHEM, LTD. (KR) 2024-01-02 US disclosed
US-20210399223-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-12-23 US disclosed
EP-3579292-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2020-08-05 EP disclosed
WO-2020060280-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2020-03-26 WO disclosed
EP-3579292-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2019-12-11 EP disclosed