SCHEMBL21587286

SCHEMBL21587286

CCNC(=O)c1ccc2c(c1)B(O)OC2

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.62
CA2 P00918 9/20 0.62
CA12 O43570 8/20 0.62
CA9 Q16790 8/20 0.62
CA4 P22748 6/20 0.62
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30616854 0.89 CA1 (0.59) CA1CA2CA12CA9CA4
SCHEMBL23133059 0.87 CA1 (0.57) CA1CA2CA12CA9CA4
SCHEMBL19977289 0.86 CA1 (0.59) CA1CA2CA12CA9CA4
SCHEMBL30616855 0.85 CA1 (0.58) CA1CA2CA12CA9CA4
SCHEMBL18360504 0.85 CA1 (0.58) CA1CA2CA12CA9CA4
SCHEMBL16906829 0.85 CA1 (0.61) CA1CA2CA12CA9CA4
SCHEMBL19582095 0.85 CA1 (0.65) CA1CA2CA12CA9CA4
SCHEMBL19608170 0.84 CA1 (0.57) CA1CA2CA12CA9CA4
SCHEMBL24121287 0.84 CA1 (0.68) CA1CA2CA12CA9CA4
SCHEMBL24459619 0.84 CA1 (0.68) CA1CA2CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116917297-A Aromatic boron-containing compounds and insulin analogues 原聚体科技公司 2023-10-20 CN claimed
CN-116917297-A Aromatic boron-containing compounds and insulin analogues 原聚体科技公司 2023-10-20 CN disclosed
EP-3578562-B1 L-VALINATE AMIDE BENZOXABOROLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES ANACOR PHARMACEUTICALS INC (US) 2021-06-23 EP disclosed
EP-3578562-A1 L-VALINATE AMIDE BENZOXABOROLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES Anacor Pharmaceuticals, Inc (US) 2019-12-11 EP disclosed