Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2A | O00443 | 14/20 | 0.71 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.57 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21586309 | 0.83 | PIK3C2A (1.00) | PIK3C2APIK3C2BPIK3C2GGAARAB9A | |
| SCHEMBL30003012 | 0.83 | PIK3C2A (1.00) | PIK3C2APIK3C2BPIK3C2GGAARAB9A | |
| SCHEMBL21586325 | 0.83 | PIK3C2A (0.85) | PIK3C2APIK3C2BPIK3C2GGAATSHR | |
| SCHEMBL30003161 | 0.83 | PIK3C2A (0.85) | PIK3C2APIK3C2BPIK3C2GGAATSHR | |
| SCHEMBL21586266 | 0.80 | PIK3C2A (0.80) | PIK3C2APIK3C2BPIK3C2GTSHRKMT2A | |
| SCHEMBL30003329 | 0.80 | PIK3C2A (0.80) | PIK3C2APIK3C2BPIK3C2GTSHRKMT2A | |
| SCHEMBL21589426 | 0.78 | PIK3C2A (0.70) | PIK3C2APIK3C2BPIK3C2GNPC1LMNA | |
| SCHEMBL21589486 | 0.77 | PIK3C2A (0.77) | PIK3C2APIK3C2BPIK3C2GGAATSHR | |
| SCHEMBL21586317 | 0.77 | PIK3C2A (0.77) | PIK3C2APIK3C2BPIK3C2GGAATSHR | |
| SCHEMBL30002964 | 0.77 | PIK3C2A (0.77) | PIK3C2APIK3C2BPIK3C2GGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019234237-A1 | HETEROCYCLIC COMPOUNDS AS CLASS II PHOSPHOINOSITIDE 3-KINASE INHIBITORS | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2019-12-12 | — | — | WO | disclosed |