⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734105 | 0.63 | — | — | |
| SCHEMBL20909952 | 0.63 | — | — | |
| SCHEMBL131324 | 0.62 | — | — | |
| SCHEMBL438299 | 0.62 | — | — | |
| SCHEMBL277061 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL3107394 | 0.61 | — | — | |
| SCHEMBL1258396 | 0.59 | — | — | |
| SCHEMBL13741247 | 0.57 | — | — | |
| SCHEMBL22728984 | 0.57 | — | — | |
| SCHEMBL1394069 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150944-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-18 | — | — | US | disclosed |
| US-20230150944-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-18 | — | — | US | disclosed |
| EP-3317271-B1 | INHIBITORS OF EZH2 (ENHANCER OF ZESTE HOMOLOG 2) | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019234158-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2019-12-12 | — | — | WO | disclosed |
| CN-109111426-A | A kind of fused bicyclic heteroaryl group or aryl compound, and application thereof | 中国科学院上海药物研究所 | 2019-01-01 | — | — | CN | disclosed |