Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.63 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.62 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11618900 | 0.87 | MAOB (0.63) | MAOBCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL914068 | 0.86 | CYP11B1 (0.49) | MAOBCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL21591553 | 0.84 | CYP11B1 (0.62) | MAOBCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL21591575 | 0.82 | MAOB (0.65) | MAOBCYP19A1KDM4ENPC1ALDH1A1 | |
| SCHEMBL20592019 | 0.81 | CYP11B1 (0.55) | MAOBCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL11620426 | 0.81 | MAOB (0.63) | MAOBCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL6557580 | 0.78 | MAOB (1.00) | MAOBCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL28990297 | 0.78 | CYP11B1 (0.54) | MAOBCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL30715535 | 0.78 | CYP11B1 (0.54) | MAOBCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL11618513 | 0.77 | CYP11B1 (0.64) | MAOBCYP11B1CYP11B2CYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807264-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238786-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2019-12-19 | — | — | WO | disclosed |