Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546296 | 0.78 | MAPT (0.56) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL29415600 | 0.78 | MAPT (0.56) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL21363791 | 0.78 | CYP3A4 (0.53) | MAPTMEN1POLBKMT2AMCL1 | |
| Water SCHEMBL28525395 | 0.76 | MAPT (0.54) | MAPTMEN1POLBKMT2AMCL1 | |
| Hydrochloric Acid SCHEMBL591717 | 0.76 | MAPT (0.54) | MAPTMEN1POLBKMT2AMCL1 | |
| Hydrochloric Acid SCHEMBL30387908 | 0.76 | MAPT (0.54) | MAPTMEN1POLBKMT2AMCL1 | |
| Hydrochloric Acid SCHEMBL29483368 | 0.76 | MAPT (0.54) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL16372578 | 0.75 | CYP3A4 (0.49) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL22657622 | 0.74 | GAA (0.37) | MAPTTAAR1CYP3A4CYP1A2 | |
| SCHEMBL7618640 | 0.74 | MAPT (0.41) | MAPTMEN1POLBKMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238046-A1 | CAMPTOTHECIN DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 青岛海洋生物医药研究院股份有限公司 | 2019-12-19 | — | — | WO | disclosed |