Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | QPCT | Q16769 | 7/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591446 | 0.91 | CYP11B1 (0.55) | CYP11B1CYP11B2QPCTGSK3BALDH1A1 | |
| SCHEMBL21592247 | 0.90 | CYP11B1 (0.46) | CYP11B1CYP11B2QPCTGSK3BALDH1A1 | |
| SCHEMBL21592273 | 0.89 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP19A1MAPTRAB9A | |
| SCHEMBL21591430 | 0.88 | CYP11B1 (0.64) | CYP11B1CYP11B2ALDH1A1CYP19A1 | |
| SCHEMBL21591568 | 0.87 | CYP11B1 (0.53) | CYP11B1CYP11B2QPCTGSK3BCYP19A1 | |
| SCHEMBL21592265 | 0.84 | CYP11B1 (0.42) | CYP11B1CYP11B2CYP19A1NPC1RAB9A | |
| SCHEMBL21591479 | 0.83 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1NPC1RAB9A | |
| SCHEMBL21591489 | 0.83 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP19A1KDM4EHPGD | |
| SCHEMBL21591435 | 0.83 | CYP11B1 (0.47) | CYP11B1CYP11B2ALDH1A1CYP19A1KDM4E | |
| SCHEMBL21591502 | 0.81 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP19A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12162863-B2 | Modulators of stimulator of interferon genes (STING) | Ryvu Therapeutics S.A. (PL) | 2024-12-10 | — | — | US | disclosed |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2022-12-22 | — | — | US | disclosed |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2022-12-22 | — | — | US | disclosed |
| WO-2019238786-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2019-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12162863-B2 | Modulators of stimulator of interferon genes (STING) | STING1, IRF3, CGAS | CYP11B1 43/4885CYP11B2 50/4885PDE4A 45/4885 |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | STING1, IRF3, CGAS | CYP11B1 43/4885CYP11B2 50/4885PDE4A 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.