Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | SIK2 | Q9H0K1 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21593328 | 0.84 | SIK2 (0.41) | SIK2MEN1KMT2AEZH2GAA | |
| SCHEMBL21593371 | 0.81 | SIK2 (0.45) | SIK2MEN1KMT2AEZH2GAA | |
| SCHEMBL21593330 | 0.80 | SIK2 (0.58) | SIK2MEN1KMT2A | |
| SCHEMBL30903189 | 0.80 | DRD4 (0.39) | SIK2MEN1KMT2AEZH2 | |
| SCHEMBL21593443 | 0.80 | SIK2 (0.41) | SIK2MEN1KMT2AEZH2GAA | |
| SCHEMBL32691557 | 0.78 | GRM5 (0.47) | GRM5SIK2KMT2AEZH2 | |
| SCHEMBL21593334 | 0.78 | SIK1 (0.42) | SIK2MEN1KMT2AGAA | |
| SCHEMBL28597676 | 0.77 | MEN1 (0.55) | GRM5MEN1KMT2AGAA | |
| SCHEMBL32691499 | 0.76 | SIK2 (0.42) | GRM5SIK2MEN1KMT2AEZH2 | |
| SCHEMBL22491132 | 0.73 | GAA (0.38) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238424-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2019-12-19 | — | — | WO | disclosed |