Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1873794 | 1.00 | GBA1 (0.66) | GBA1ALDH1A1FUCA1SLC18A3ACHE | |
| SCHEMBL21593411 | 1.00 | GBA1 (0.66) | GBA1ALDH1A1FUCA1SLC18A3ACHE | |
| SCHEMBL21593408 | 1.00 | GBA1 (0.66) | GBA1ALDH1A1FUCA1SLC18A3ACHE | |
| SCHEMBL6042430 | 1.00 | GBA1 (0.66) | GBA1ALDH1A1FUCA1SLC18A3ACHE | |
| SCHEMBL7236741 | 0.88 | CCR3 (0.57) | GBA1ALDH1A1FUCA1SLC18A3ACHE | |
| SCHEMBL1315584 | 0.88 | GBA1 (0.66) | GBA1ALDH1A1FUCA1SLC18A3ACHE | |
| SCHEMBL1315585 | 0.88 | GBA1 (0.66) | GBA1ALDH1A1FUCA1SLC18A3ACHE | |
| SCHEMBL458459 | 0.88 | GBA1 (0.66) | GBA1ALDH1A1FUCA1SLC18A3ACHE | |
| SCHEMBL505547 | 0.88 | GBA1 (0.66) | GBA1ALDH1A1FUCA1SLC18A3ACHE | |
| SCHEMBL29716681 | 0.88 | GBA1 (0.66) | GBA1ALDH1A1FUCA1SLC18A3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238424-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2019-12-19 | — | — | WO | disclosed |