Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 19/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24490150 | 0.87 | TOP1 (0.63) | TOP1SLC2A1 | |
| SCHEMBL21592055 | 0.80 | TOP1 (0.69) | TOP1SLC2A1 | |
| SCHEMBL23255529 | 0.80 | TOP1 (0.68) | TOP1SLC2A1 | |
| SCHEMBL23235256 | 0.80 | TOP1 (0.68) | TOP1SLC2A1 | |
| SCHEMBL23235261 | 0.79 | TOP1 (0.67) | TOP1SLC2A1 | |
| SCHEMBL21591951 | 0.79 | TOP1 (0.71) | TOP1SLC2A1 | |
| SCHEMBL24490052 | 0.76 | TOP1 (0.65) | TOP1SLC2A1 | |
| SCHEMBL21593872 | 0.75 | TOP1 (0.71) | TOP1SLC2A1 | |
| SCHEMBL23255589 | 0.75 | TOP1 (0.73) | TOP1SLC2A1 | |
| SCHEMBL23255710 | 0.75 | TOP1 (0.72) | TOP1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238046-A1 | CAMPTOTHECIN DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 青岛海洋生物医药研究院股份有限公司 | 2019-12-19 | — | — | WO | disclosed |