Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16438084 | 0.79 | PDE2A (0.42) | PDE2ASLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL13778630 | 0.79 | SLC6A2 (0.37) | PDE2ASLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL14373872 | 0.79 | SLC6A2 (0.37) | PDE2ASLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL13778645 | 0.79 | SLC6A2 (0.37) | PDE2ASLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL16166542 | 0.79 | PDE2A (0.59) | PDE2ASLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL22615057 | 0.78 | PDE2A (0.41) | PDE2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL27823387 | 0.77 | PDE2A (0.40) | PDE2A | |
| SCHEMBL27724297 | 0.74 | PDE2A (0.42) | PDE2A | |
| SCHEMBL27724296 | 0.74 | PDE2A (0.42) | PDE2A | |
| SCHEMBL30440392 | 0.73 | UGT2B7 (0.52) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238057-A1 | APPLICATION OF FSO2N3 IN PREPARATION OF AZIDE | 中国科学院上海有机化学研究所 | 2019-12-19 | — | — | WO | disclosed |