Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.88 |
| ▸ | LCK | P06239 | 1/20 | 0.88 |
| ▸ | FYN | P06241 | 1/20 | 0.88 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11400525 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL462200 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL8061222 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL2848522 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL11246672 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL21197465 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL2916665 | 1.00 | — | — | |
| Acetic Acid SCHEMBL20553940 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL20537337 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL11962949 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201935-A | Condensed imide derivative | 正大天晴药业集团股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2024037616-A1 | COMPOUND CONTAINING CYCLOHEXYL | 正大天晴药业集团股份有限公司 | 2024-02-22 | — | — | WO | disclosed |
| US-11845874-B2 | Radiation curable inkjet inks for interior decoration | AGFA NV (BE) | 2023-12-19 | — | — | US | disclosed |
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |
| CN-112697892-B | Method for quantitatively detecting cyclic alkyl sulfonate component and residual oil sulfonate component in petroleum production liquid | 中国石油天然气股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-113302244-B | Radiation curable inkjet inks for interior decoration | 爱克发有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-112334551-B | Acylphosphine oxide initiators | 爱克发有限公司 | 2022-11-08 | — | — | CN | disclosed |
| US-20220119662-A1 | RADIATION CURABLE INKJET INKS FOR INTERIOR DECORATION | AGFA NV (BE) | 2022-04-21 | — | — | US | disclosed |
| EP-3914655-A1 | RADIATION CURABLE INKJET INKS FOR INTERIOR DECORATION | AGFA NV (BE) | 2021-12-01 | — | — | EP | disclosed |
| CN-113302244-A | Radiation curable inkjet inks for interior decoration | 爱克发有限公司 | 2021-08-24 | — | — | CN | disclosed |
| EP-3810710-A1 | ACYLPHOSPHINEOXIDE INITIATORS | AGFA NV (BE) | 2021-04-28 | — | — | EP | disclosed |
| CN-112334551-A | Acylphosphine oxide initiators | 爱克发有限公司 | 2021-02-05 | — | — | CN | disclosed |
| WO-2020152037-A1 | RADIATION CURABLE INKJET INKS FOR INTERIOR DECORATION | AGFA NV (BE) | 2020-07-30 | — | — | WO | disclosed |
| WO-2019243039-A1 | ACYLPHOSPHINEOXIDE INITIATORS | AGFA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
| CN-103792309-B | The preparation method of Acid Orange II standard detection sample | SHENYANG PRODUCT QUALITY SUPERVISION AND INSPECTION INSTITUTE (CN) | 2015-08-19 | — | — | CN | disclosed |
| CN-103792309-A | Preparation method of standard test specimen for acid orange II | SHENYANG PRODUCT QUALITY SUPERVISION AND INSPECTION INST | 2014-05-14 | — | — | CN | disclosed |