Tyrosine

Tyrosine

SCHEMBL21596546

NC(CS)C(=O)O.NC(Cc1ccc(O)cc1)C(=O)O.NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.83
PTGS1 P23219 4/20 0.59
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
XIAP P98170 1/20 0.59
ALOX15 P16050 3/20 0.56
HIF1A Q16665 3/20 0.56
KDM4E B2RXH2 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
USP2 O75604 1/20 0.56
EGFR P00533 1/20 0.56
LCK P06239 1/20 0.56
FYN P06241 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
HTR2A P28223 1/20 0.56
PTGS2 P35354 1/20 0.56
RECQL P46063 1/20 0.56
HSD17B10 Q99714 1/20 0.56
SLC7A11 Q9UPY5 1/20 0.55
TPH1 P17752 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL5707691 1.00 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL27748337 1.00 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1456075 1.00 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL8981412 1.00 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL9542800 1.00 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL12471720 1.00 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL12471725 1.00 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL3496039 0.95 SLC7A5 (0.75) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL5027400 0.94 SLC7A5 (0.73) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL3796383 0.94 SLC7A5 (0.73) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114752369-A Preparation method of ratio-type fluorescent probe and application of ratio-type fluorescent probe in tyrosinase detection 中国石油大学(华东) 2022-07-15 CN claimed
EP-3811052-B1 SINGLE PARTICLE AUTOMATED RAMAN TRAPPING ANALYSIS IMPERIAL COLLEGE INNOVATIONS LTD (GB) 2023-07-26 EP disclosed
CN-114752369-A Preparation method of ratio-type fluorescent probe and application of ratio-type fluorescent probe in tyrosinase detection 中国石油大学(华东) 2022-07-15 CN disclosed
EP-3816183-A1 ANTIBODY LIBRARY AND ANTIBODY SCREENING METHOD USING SAME Mogam Institute for Biomedical Research (KR) 2021-05-05 EP disclosed
EP-3811052-A1 SINGLE PARTICLE AUTOMATED RAMAN TRAPPING ANALYSIS Imperial College of Science, Technology and Medicine (GB) 2021-04-28 EP disclosed
WO-2019243375-A1 SINGLE PARTICLE AUTOMATED RAMAN TRAPPING ANALYSIS IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) 2019-12-26 WO disclosed