Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | REV1 | Q9UBZ9 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21597578 | 0.90 | CNR2 (0.43) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21597436 | 0.88 | CNR2 (0.44) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21603644 | 0.88 | CNR2 (0.44) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL27416460 | 0.88 | CNR2 (0.44) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21604170 | 0.88 | CNR2 (0.44) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21597755 | 0.87 | CNR2 (0.42) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21597556 | 0.83 | CXCR2 (0.51) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21597693 | 0.83 | CNR2 (0.38) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21597113 | 0.79 | CNR2 (0.50) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21597125 | 0.76 | CNR2 (0.65) | CNR2CNR1KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810606-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |