Dibenzoylmethane

Dibenzoylmethane

SCHEMBL21597905

O=C(CC(=O)c1ccccc1)c1ccccc1.[Mn]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.94
HPGD P15428 3/20 0.94
KMT2A Q03164 3/20 0.94
MAPK1 P28482 3/20 0.94
MAPT P10636 3/20 0.94
CYP3A4 P08684 2/20 0.94
TDP1 Q9NUW8 2/20 0.94
ALOX15 P16050 2/20 0.94
SMN1; SMN2 Q16637 2/20 0.94
CES1 P23141 2/20 0.94
KDM4E B2RXH2 1/20 0.94
ALDH1A1 P00352 3/20 0.71
NPC1 O15118 3/20 0.71
PLOD2 O00469 2/20 0.71
HIF1A Q16665 2/20 0.71
RAB9A P51151 2/20 0.71
PLOD3 O60568 1/20 0.71
CYP1A2 P05177 1/20 0.71
CYP2D6 P10635 1/20 0.71
CYP2C9 P11712 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzoylmethane SCHEMBL39582 0.97 MEN1 (1.00) MEN1HPGDKMT2AMAPK1MAPT
Dibenzoylmethane SCHEMBL10356288 0.97 MEN1 (1.00) MEN1HPGDKMT2AMAPK1MAPT
Dibenzoylmethane SCHEMBL1704711 0.97 MEN1 (1.00) MEN1HPGDKMT2AMAPK1MAPT
SCHEMBL2005451 0.94 MEN1 (0.94) MEN1HPGDKMT2AMAPK1MAPT
Dibenzoylmethane SCHEMBL531257 0.94 MEN1 (0.94) MEN1HPGDKMT2AMAPK1MAPT
Dibenzoylmethane SCHEMBL1628627 0.94 MEN1 (0.94) MEN1HPGDKMT2AMAPK1MAPT
Dibenzoylmethane SCHEMBL6598370 0.94 MEN1 (0.94) MEN1HPGDKMT2AMAPK1MAPT
Dibenzoylmethane SCHEMBL17287926 0.94 MEN1 (0.94) MEN1HPGDKMT2AMAPK1MAPT
Dibenzoylmethane SCHEMBL6249492 0.94 MEN1 (0.94) MEN1HPGDKMT2AMAPK1MAPT
Dibenzoylmethane SCHEMBL11588084 0.94 MEN1 (0.94) MEN1HPGDKMT2AMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3810723-B1 COATING COMPOSITION PPG EUROPE B V (NL) 2024-02-21 EP disclosed
EP-3810723-A1 COATING COMPOSITION PPG Europe B.V. (NL) 2021-04-28 EP disclosed
WO-2019243546-A1 COATING COMPOSITION PPG EUROPE B.V. (NL) 2019-12-26 WO disclosed