Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21597984 | 0.79 | TSHR (0.41) | HSD17B10CYP2C19KDM4EL3MBTL1KMT2A | |
| SCHEMBL21597980 | 0.77 | EDNRA (0.42) | KDM4ESMN1; SMN2L3MBTL1KMT2APOLB | |
| SCHEMBL9108563 | 0.69 | SMN1; SMN2 (0.52) | HSD17B10CYP2C19KDM4ESMN1; SMN2HTT | |
| SCHEMBL13414995 | 0.69 | SMN1; SMN2 (0.52) | HSD17B10CYP2C19KDM4ESMN1; SMN2HTT | |
| SCHEMBL2970074 | 0.68 | HSD17B10 (0.43) | HSD17B10CYP2C19KDM4ESMN1; SMN2HTT | |
| SCHEMBL16104914 | 0.67 | MAPT (0.54) | HSD17B10CYP2C19KDM4ESMN1; SMN2HTT | |
| SCHEMBL28584612 | 0.67 | NAMPT (0.61) | HSD17B10CYP2C19KDM4ESMN1; SMN2HTT | |
| SCHEMBL5868999 | 0.67 | SLC18A3 (0.63) | HSD17B10CYP2C19KDM4ESMN1; SMN2HTT | |
| SCHEMBL861674 | 0.67 | SMN1; SMN2 (0.84) | HSD17B10CYP2C19KDM4ESMN1; SMN2HTT | |
| SCHEMBL22335133 | 0.65 | KDM1A (0.63) | HSD17B10SMN1; SMN2L3MBTL1NAPRTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243576-A1 | GLUCOSE-SENSITIVE PEPTIDE HORMONES | GUBRA APS (DK) | 2019-12-26 | — | — | WO | disclosed |