Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 5/20 | 0.51 |
| ▸ | ACE | P12821 | 5/20 | 0.51 |
| ▸ | CPA1 | P15085 | 2/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21598076 | 1.00 | FOLH1 (0.52) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL152798 | 0.91 | FOLH1 (0.60) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL161943 | 0.91 | FOLH1 (0.60) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL160418 | 0.91 | FOLH1 (0.60) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL12379290 | 0.89 | MME (0.61) | MMEACECPA1ACE2PPARG | |
| Hydrochloric Acid SCHEMBL2523741 | 0.89 | FOLH1 (0.59) | FOLH1MMEACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL5052199 | 0.89 | FOLH1 (0.59) | FOLH1MMEACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL17666593 | 0.89 | FOLH1 (0.59) | FOLH1MMEACECPA1ACE2 | |
| Water SCHEMBL27589726 | 0.89 | FOLH1 (0.59) | FOLH1MMEACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL15105483 | 0.89 | FOLH1 (0.59) | FOLH1MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810169-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BicycleTX Limited (GB) | 2021-04-28 | — | — | EP | claimed |
| CN-112601539-A | Bicyclic peptide ligands specific for bindin-4 | 拜斯科技术开发有限公司 | 2021-04-02 | — | — | CN | claimed |
| WO-2019243832-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BICYCLETX LIMITED (GB) | 2019-12-26 | — | — | WO | claimed |
| EP-4588934-A2 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BicycleTX Limited (GB) | 2025-07-23 | — | — | EP | disclosed |
| EP-4464715-A2 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BicycleTx Limited (GB) | 2024-11-20 | — | — | EP | disclosed |