Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | FRK | P42685 | 1/20 | 0.39 |
| ▸ | BLK | P51451 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21600818 | 0.92 | AAK1 (0.39) | FYNSRCPTK6ABL1AAK1 | |
| SCHEMBL21600810 | 0.90 | PTK6 (0.38) | FYNSRCPTK6ABL1ATR | |
| SCHEMBL25139995 | 0.88 | FYN (0.41) | FYNSRCPTK6ABL1ATR | |
| SCHEMBL21600789 | 0.87 | FYN (0.41) | FYNSRCPTK6ABL1AAK1 | |
| SCHEMBL21600846 | 0.86 | PTK6 (0.37) | FYNSRCPTK6ABL1ATR | |
| SCHEMBL6164833 | 0.85 | KDM4E (0.41) | AAK1LMNA | |
| SCHEMBL6166440 | 0.85 | KDM4E (0.39) | AAK1WDR5DRD2LMNA | |
| SCHEMBL6164404 | 0.84 | MEN1 (0.42) | LMNA | |
| SCHEMBL21596984 | 0.82 | FYN (0.43) | FYNSRCPTK6ABL1AAK1 | |
| SCHEMBL30044654 | 0.82 | FYN (0.43) | FYNSRCPTK6ABL1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019242689-A1 | CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | 北京赛特明强医药科技有限公司 | 2019-12-26 | — | — | WO | disclosed |