Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 4/20 | 0.39 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267121 | 0.94 | OR51E2 (0.48) | OR51E2MAPK1SLC13A3EGLN1LMNA | |
| SCHEMBL1062796 | 0.85 | OR51E2 (0.58) | OR51E2MAPK1SLC13A3EGLN1LMNA | |
| SCHEMBL10961683 | 0.84 | OR51E2 (0.56) | OR51E2MAPK1SLC13A3EGLN1LMNA | |
| SCHEMBL10957816 | 0.84 | OR51E2 (0.56) | OR51E2MAPK1SLC13A3EGLN1LMNA | |
| SCHEMBL10963354 | 0.84 | OR51E2 (0.56) | OR51E2MAPK1SLC13A3EGLN1LMNA | |
| SCHEMBL10960960 | 0.84 | OR51E2 (0.56) | OR51E2MAPK1SLC13A3EGLN1LMNA | |
| SCHEMBL10964715 | 0.84 | OR51E2 (0.56) | OR51E2MAPK1SLC13A3EGLN1LMNA | |
| SCHEMBL10959418 | 0.84 | OR51E2 (0.56) | OR51E2MAPK1SLC13A3EGLN1LMNA | |
| SCHEMBL10962384 | 0.84 | OR51E2 (0.56) | OR51E2MAPK1SLC13A3EGLN1LMNA | |
| SCHEMBL10961559 | 0.84 | OR51E2 (0.56) | OR51E2MAPK1SLC13A3EGLN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019241851-A1 | INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | LA TROBE UNIVERSITY (AU) | 2019-12-26 | — | — | WO | disclosed |