Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2145956 | 1.00 | AURKA (0.59) | AURKAAURKB | |
| SCHEMBL2149146 | 0.90 | AURKA (0.72) | AURKAAURKB | |
| SCHEMBL2148668 | 0.90 | AURKA (0.72) | AURKAAURKB | |
| SCHEMBL2171510 | 0.88 | AURKA (0.69) | AURKAAURKB | |
| SCHEMBL2224220 | 0.88 | AURKA (0.69) | AURKAAURKB | |
| SCHEMBL2162306 | 0.88 | AURKA (0.60) | AURKAAURKB | |
| SCHEMBL2169261 | 0.88 | AURKA (0.73) | AURKAAURKB | |
| SCHEMBL2148775 | 0.88 | AURKA (0.61) | AURKAAURKB | |
| SCHEMBL2172255 | 0.87 | AURKA (0.67) | AURKAAURKB | |
| SCHEMBL2148774 | 0.87 | AURKA (0.58) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088045-A1 | AURORA KINASE COMPOUNDS AND METHODS OF THEIR USE | AMBIT BIOSCIENCES CORPORATION (US) | 2011-07-21 | — | — | WO | disclosed |