Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.46 |
| ▸ | NPY1R | P25929 | 9/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.46 |
| ▸ | NPY2R | P49146 | 5/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | SCTR | P47872 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2159226 | 0.90 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2RMC4R | |
| SCHEMBL29777920 | 0.86 | NPY4R (0.48) | NPY4RNPY1RNPY5RNPY2RMC4R | |
| SCHEMBL29808185 | 0.86 | NPY4R (0.48) | NPY4RNPY1RNPY5RNPY2RMC4R | |
| SCHEMBL9294926 | 0.86 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2RGLP1R | |
| SCHEMBL32682323 | 0.85 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RGLP1R | |
| SCHEMBL30512603 | 0.84 | MC4R (0.47) | NPY4RNPY1RNPY5RNPY2RMC4R | |
| SCHEMBL30656927 | 0.83 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL30966840 | 0.83 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30524330 | 0.83 | GLP1R (0.50) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL30873807 | 0.82 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985402-B2 | Ultrasound contrast agent of peptide monomers; peptide vectors having high KDR binding affinity; gas filled microvesicle containing a fluorinated gas and a phospholipid | BRACCO SUISSE SA (CH) | 2011-07-26 | — | — | US | disclosed |
| US-20080152594-A1 | TARGETING VECTOR-PHOSPHOLIPID CONJUGATES | BRACCO SUISSE SA (CH) | 2008-06-26 | — | — | US | disclosed |