Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21602978 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1FAAHSOAT1MEN1 | |
| SCHEMBL4358496 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1FAAHSOAT1MEN1 | |
| SCHEMBL8459953 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1FAAHSOAT1MEN1 | |
| SCHEMBL28901737 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1FAAHSOAT1MEN1 | |
| SCHEMBL16302453 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1FAAHSOAT1MEN1 | |
| SCHEMBL13448422 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1FAAHSOAT1MEN1 | |
| SCHEMBL5691700 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1FAAHSOAT1MEN1 | |
| SCHEMBL23273576 | 0.97 | — | — | |
| SCHEMBL7958181 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28461781 | 0.95 | SPHK2 (0.48) | SPHK2SPHK1FAAHSOAT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020002083-A1 | SUBSTITUTED HETEROCYCLIC PYRROLONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-02 | — | — | WO | disclosed |