⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294798 | 0.84 | EGLN2 (0.41) | — | |
| SCHEMBL154932 | 0.74 | — | — | |
| SCHEMBL29740320 | 0.74 | — | — | |
| SCHEMBL24942537 | 0.72 | EGLN2 (0.36) | — | |
| Ammonia Solution, Strong SCHEMBL22960694 | 0.71 | — | — | |
| SCHEMBL22960697 | 0.71 | — | — | |
| SCHEMBL22960695 | 0.71 | — | — | |
| SCHEMBL732152 | 0.70 | — | — | |
| SCHEMBL1777965 | 0.70 | — | — | |
| SCHEMBL3906820 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127297-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | PFIZER INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2019243527-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |