Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21603632 | 0.82 | MAPT (0.60) | KDM4EMAPTHSD17B10FLT3ALDH1A1 | |
| SCHEMBL21603714 | 0.81 | KDM4E (0.58) | KDM4EMAPTHSD17B10FLT3ALDH1A1 | |
| SCHEMBL21604205 | 0.80 | MAPT (0.57) | KDM4EMAPTHSD17B10FLT3ALDH1A1 | |
| SCHEMBL21603658 | 0.80 | KDM4E (0.57) | KDM4EMAPTHSD17B10FLT3ALDH1A1 | |
| SCHEMBL21604179 | 0.77 | MAPT (0.67) | KDM4EMAPTHSD17B10FLT3ALDH1A1 | |
| SCHEMBL21597309 | 0.77 | KDM4E (0.51) | KDM4EMAPTHSD17B10FLT3ALDH1A1 | |
| SCHEMBL21604053 | 0.75 | KDM4E (0.76) | KDM4EMAPTHSD17B10FLT3ALDH1A1 | |
| SCHEMBL21603769 | 0.74 | KDM4E (0.62) | KDM4EMAPTHSD17B10FLT3ALDH1A1 | |
| SCHEMBL21604247 | 0.74 | FLT3 (0.61) | KDM4EMAPTHSD17B10FLT3ALDH1A1 | |
| SCHEMBL3914277 | 0.73 | FLT3 (0.77) | KDM4EMAPTHSD17B10FLT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |