Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21597259 | 0.86 | CNR2 (0.41) | CNR2CNR1REV1MAPTALDH1A1 | |
| SCHEMBL21603848 | 0.82 | CNR2 (0.53) | CNR2CNR1REV1MAPTKMT2A | |
| SCHEMBL21597815 | 0.80 | MAPT (0.57) | MAPTALDH1A1HPGDMAPK1KMT2A | |
| SCHEMBL21603687 | 0.76 | CNR2 (0.71) | CNR2CNR1REV1MAPTALDH1A1 | |
| SCHEMBL21603668 | 0.76 | CNR2 (0.49) | CNR2CNR1REV1MAPTKMT2A | |
| SCHEMBL21603669 | 0.75 | CNR2 (0.53) | CNR2CNR1REV1MAPTKMT2A | |
| SCHEMBL21603860 | 0.74 | CNR2 (0.52) | CNR2CNR1REV1MAPTKMT2A | |
| SCHEMBL21603679 | 0.73 | CNR2 (0.51) | CNR2CNR1REV1MAPTKMT2A | |
| SCHEMBL21603765 | 0.73 | CNR2 (0.77) | CNR2CNR1REV1MAPTALDH1A1 | |
| SCHEMBL21604028 | 0.73 | CNR2 (0.70) | CNR2CNR1REV1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |