Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21597774 | 0.84 | CNR2 (0.45) | CNR2CNR1MAPTHTTKDM4E | |
| SCHEMBL21597174 | 0.84 | CNR2 (0.48) | CNR2CNR1MAPTHTTKDM4E | |
| SCHEMBL21597625 | 0.76 | CNR2 (0.46) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL21604195 | 0.74 | CNR2 (0.45) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL21597165 | 0.74 | CNR2 (0.45) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL21603675 | 0.73 | CNR2 (0.52) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL21603709 | 0.73 | CNR2 (0.48) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL21597670 | 0.72 | MAPT (0.47) | CNR2CNR1MAPTHTTKDM4E | |
| SCHEMBL21597806 | 0.72 | CNR2 (0.46) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL28920828 | 0.71 | CNR2 (0.50) | CNR2CNR1MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |