Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | OGA | O60502 | 13/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.33 |
| ▸ | FEN1 | P39748 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21603323 | 0.84 | GRM5 (0.43) | GRM5OGAALOX5APFEN1 | |
| SCHEMBL84582 | 0.77 | GRM5 (0.50) | GRM5ALOX5APFEN1 | |
| SCHEMBL21607089 | 0.72 | OGA (0.47) | GRM5OGAALOX5APFEN1 | |
| SCHEMBL21605880 | 0.71 | OGA (0.37) | GRM5OGAALOX5APFEN1 | |
| SCHEMBL21605959 | 0.71 | ALOX5AP (0.37) | GRM5OGAALOX5APFEN1 | |
| SCHEMBL21605832 | 0.71 | ALOX5AP (0.37) | GRM5OGAALOX5APFEN1 | |
| SCHEMBL21603370 | 0.71 | GRM5 (0.35) | GRM5OGAALOX5APFEN1 | |
| SCHEMBL21603309 | 0.71 | GRM5 (0.35) | GRM5OGAALOX5APFEN1 | |
| SCHEMBL21603364 | 0.71 | GRM5 (0.35) | GRM5OGAALOX5APFEN1 | |
| SCHEMBL23871278 | 0.69 | OGA (0.38) | GRM5OGAALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243526-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |