SCHEMBL21609151

SCHEMBL21609151

COCc1cc(OC)c2c(NSc3c(OC)cccc3OC)noc2c1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT7 O95251 20/20 0.47
KAT6A Q92794 20/20 0.47
KAT6B Q8WYB5 11/20 0.47
KAT5 Q92993 8/20 0.46
KAT8 Q9H7Z6 8/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609084 0.90 KAT7 (0.46) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21609036 0.85 KAT7 (0.41) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21609078 0.83 KAT6A (0.42) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817445 0.82 KAT6A (0.41) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817402 0.81 KAT7 (0.68) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817429 0.81 KAT7 (0.69) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21609190 0.79 KAT6A (0.41) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31605632 0.78 KAT6A (0.74) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21609033 0.78 KAT6A (0.74) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL26517573 0.76 KAT6A (0.46) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 WO disclosed