SCHEMBL21609702

SCHEMBL21609702

CC(C)(C)OC(=O)NCCOc1cc(N)ccc1N

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.52
CA1 P00915 5/20 0.52
CA2 P00918 5/20 0.52
CA9 Q16790 5/20 0.52
IDO1 P14902 3/20 0.45
PDK2 Q15119 1/20 0.43
SCN9A Q15858 1/20 0.43
CYP1A1 P04798 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2B6 P20813 1/20 0.43
CYP2C19 P33261 1/20 0.43
CYP3A43 Q9HB55 1/20 0.43
BRD4 O60885 2/20 0.41
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
NQO2 P16083 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609699 0.91 CA12 (0.55) CA12CA1CA2CA9CYP1A1
SCHEMBL21609701 0.90 CA12 (0.52) CA12CA1CA2CA9IDO1
SCHEMBL1531272 0.87 CA12 (0.50) CA12CA1CA2CA9IDO1
SCHEMBL7449161 0.87 CA12 (0.50) CA12CA1CA2CA9IDO1
SCHEMBL12693236 0.87 CA12 (0.50) CA12CA1CA2CA9IDO1
SCHEMBL31759032 0.86 CA1 (0.49) CA12CA1CA2CA9IDO1
SCHEMBL447122 0.86 CA12 (0.46) CA12CA1CA2CA9IDO1
SCHEMBL23629002 0.85 CA12 (0.48) CA12CA1CA2CA9IDO1
SCHEMBL4007583 0.85 CA12 (0.50) CA12CA1CA2CA9IDO1
SCHEMBL18034625 0.84 CA12 (0.47) CA12CA1CA2CA9IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019244939-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME, AND PRODUCTION METHOD FOR SAID LIQUID CRYSTAL DISPLAY ELEMENT, AND DIAMINE COMPOUND 日産化学株式会社 2019-12-26 WO disclosed