Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 14/20 | 0.40 |
| ▸ | VNN1 | O95497 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21611067 | 1.00 | TTK (0.44) | TTKLRRK2VNN1DYRK1AGRM5 | |
| SCHEMBL21609963 | 0.91 | TTK (0.52) | TTKLRRK2DYRK1AGRM5 | |
| SCHEMBL21611045 | 0.88 | TTK (0.47) | TTKLRRK2DYRK1A | |
| SCHEMBL21611041 | 0.88 | TTK (0.47) | TTKLRRK2DYRK1A | |
| SCHEMBL21611020 | 0.86 | DYRK1A (0.46) | TTKLRRK2DYRK1A | |
| SCHEMBL21611023 | 0.86 | DYRK1A (0.46) | TTKLRRK2DYRK1A | |
| SCHEMBL21611065 | 0.84 | TTK (0.56) | TTKLRRK2DYRK1AGRM5 | |
| SCHEMBL21611049 | 0.80 | TTK (0.53) | TTKLRRK2DYRK1A | |
| SCHEMBL22280242 | 0.79 | TTK (0.59) | TTKLRRK2 | |
| SCHEMBL21611051 | 0.79 | TTK (0.55) | TTKLRRK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220106307-A1 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2022-04-07 | — | — | US | claimed |
| US-11117892-B2 | Pyrrolo-pyridine derivative compound, method for preparing same, and pharmaceutical composition containing same as active ingredient for prevention or treatment of protein kinase-related diseases | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION | 2021-09-14 | — | — | US | claimed |
| US-20200207756-A1 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-07-02 | — | — | US | claimed |
| EP-3604304-A1 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2020-02-05 | — | — | EP | claimed |
| CN-110662745-A | Pyrrolopyridine derivatives, process for preparing the same, and pharmaceutical composition for preventing or treating protein kinase-associated diseases comprising the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2020-01-07 | — | — | CN | claimed |
| US-20220106307-A1 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2022-04-07 | — | — | US | disclosed |
| US-11117892-B2 | Pyrrolo-pyridine derivative compound, method for preparing same, and pharmaceutical composition containing same as active ingredient for prevention or treatment of protein kinase-related diseases | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION | 2021-09-14 | — | — | US | disclosed |
| US-11117892-B2 | Pyrrolo-pyridine derivative compound, method for preparing same, and pharmaceutical composition containing same as active ingredient for prevention or treatment of protein kinase-related diseases | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION | 2021-09-14 | — | — | US | disclosed |
| CN-110662745-B | Pyrrolopyridine derivatives, process for producing the same, and pharmaceutical composition for preventing or treating protein kinase-associated diseases | 大邱庆北尖端医疗产业振兴财团 | 2021-08-03 | — | — | CN | disclosed |
| US-20200207756-A1 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-07-02 | — | — | US | disclosed |
| US-20200207756-A1 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-07-02 | — | — | US | disclosed |
| EP-3604304-A1 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2020-02-05 | — | — | EP | disclosed |
| CN-110662745-A | Pyrrolopyridine derivatives, process for preparing the same, and pharmaceutical composition for preventing or treating protein kinase-associated diseases comprising the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2020-01-07 | — | — | CN | disclosed |
| WO-2018174650-A9 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | 재단법인 대구경북첨단의료산업진흥재단 | 2020-01-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106307-A1 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | DYRK1A, DYRK2, DYRK1B | TTK 100/4885LRRK2 298/4885VNN1 4229/4885 |
| US-11117892-B2 | Pyrrolo-pyridine derivative compound, method for preparing same, and pharmaceutical composition containing same as active ingredient for prevention or treatment of protein kinase-related diseases | DYRK1A, DYRK2, DYRK1B | TTK 100/4885LRRK2 298/4885VNN1 4229/4885 |
| US-20200207756-A1 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | DYRK1A, DYRK2, DYRK4 | TTK 93/4885LRRK2 383/4885VNN1 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.