Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 19/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.39 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21613463 | 0.86 | GRIN2B (0.41) | GRIN2BGRIN1 | |
| SCHEMBL21613443 | 0.81 | GRIN2B (0.48) | GRIN2BGRIN1 | |
| SCHEMBL21613618 | 0.81 | GRIN2B (0.38) | GRIN2BGRIN1VRK1 | |
| SCHEMBL21613612 | 0.80 | GRIN2B (0.43) | GRIN2BGRIN1 | |
| SCHEMBL21613606 | 0.79 | PSMB5 (0.44) | GRIN2B | |
| SCHEMBL21613614 | 0.76 | GRIN2B (0.44) | GRIN2BGRIN1 | |
| SCHEMBL21613617 | 0.76 | GRIN2B (0.44) | GRIN2BGRIN1 | |
| SCHEMBL21613621 | 0.76 | GRIN2B (0.44) | GRIN2BGRIN1 | |
| SCHEMBL21613526 | 0.76 | GRIN2B (0.34) | GRIN2BGRIN1VRK1 | |
| SCHEMBL21613480 | 0.75 | EGLN1 (0.45) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319963-B1 | SUBSTITUTED 4-AZAINDOLES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-01-08 | — | — | EP | disclosed |