Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1836487 | 0.93 | NPC1 (0.38) | NPC1RAB9AMAPTHTTNR3C1 | |
| SCHEMBL1836408 | 0.89 | NPC1 (0.40) | NPC1RAB9AMAPTHTTNR3C1 | |
| SCHEMBL1833339 | 0.81 | SKP2 (0.35) | NPC1RAB9AMAPTTSHRELANE | |
| SCHEMBL1827823 | 0.79 | MAPT (0.34) | NPC1RAB9AMAPTNR3C1PGR | |
| SCHEMBL1827964 | 0.78 | MAPT (0.37) | NPC1RAB9AMAPTNR3C1PGR | |
| SCHEMBL1828519 | 0.77 | MAPT (0.38) | NPC1RAB9AMAPTHTTNR3C1 | |
| SCHEMBL1829024 | 0.74 | MAPT (0.35) | NPC1RAB9AMAPTNR3C1PGR | |
| SCHEMBL2161509 | 0.74 | POLB (0.43) | NPC1RAB9AMAPTTSHRMEN1 | |
| SCHEMBL1830804 | 0.74 | MAPT (0.39) | NPC1RAB9AMAPTNR3C1PGR | |
| SCHEMBL1833851 | 0.73 | MAPT (0.38) | NPC1RAB9AMAPTNR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | NPC1 2992/4885RAB9A 405/4885MAPT 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.