Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.85 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616860 | 0.92 | BACE1 (1.00) | BACE1HRH3KCNH2HRH4 | |
| SCHEMBL23697924 | 0.84 | BACE1 (0.79) | BACE1HRH3KCNH2HRH4 | |
| SCHEMBL23671488 | 0.82 | BACE1 (0.68) | BACE1 | |
| SCHEMBL23671493 | 0.81 | BACE1 (0.58) | BACE1 | |
| SCHEMBL21616863 | 0.81 | BACE1 (1.00) | BACE1HRH3 | |
| SCHEMBL21622469 | 0.81 | BACE1 (1.00) | BACE1HRH3 | |
| SCHEMBL21616864 | 0.80 | BACE1 (1.00) | BACE1HRH3 | |
| SCHEMBL23671502 | 0.79 | BACE1 (0.69) | BACE1 | |
| SCHEMBL21616861 | 0.79 | BACE1 (1.00) | BACE1HRH3 | |
| SCHEMBL23671489 | 0.79 | BACE1 (0.58) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820862-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2021-05-19 | — | — | EP | claimed |
| WO-2020011848-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2020-01-16 | — | — | WO | claimed |