SCHEMBL21623914

SCHEMBL21623914

CCNNC(=O)CC#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21623910 0.79 MCL1 (0.55)
SCHEMBL9202834 0.79 MCL1 (0.58)
SCHEMBL17728313 0.78 MCL1 (0.53)
SCHEMBL21623912 0.77 MCL1 (0.52)
SCHEMBL215502 0.76
SCHEMBL11012909 0.74
SCHEMBL9204813 0.74 MCL1 (0.56)
SCHEMBL3538392 0.72
SCHEMBL9202307 0.71 MCL1 (0.52)
SCHEMBL12703485 0.71 MCL1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912648-B2 Method for preparing C-H acidic (meth)acrylates EVONIK OPERATIONS GMBH (DE) 2024-02-27 US disclosed
CN-112424161-B Process for preparing C-H acidic (meth) acrylic compounds 赢创运营有限公司 2023-08-04 CN disclosed
CN-112424163-B CH-acidic methacrylates for preparing aqueous polymer dispersions 赢创运营有限公司 2023-06-23 CN disclosed
US-20210332005-A1 CH-ACIDIC METHACRYLIC ESTERS FOR THE PREPARATION OF AQUEOUS POLYMER DISPERSIONS EVONIK OPERATIONS GMBH (DE) 2021-10-28 US disclosed
CN-112424163-A CH-acidic methacrylates for preparing aqueous polymer dispersions 赢创运营有限公司 2021-02-26 CN disclosed
CN-112424161-A Method for producing C-H acidic (meth) acrylic compounds 赢创运营有限公司 2021-02-26 CN disclosed
EP-3655387-B1 CH-ACIDIC METHACRYLIC ESTERS FOR THE PREPARATION OF AQUEOUS POLYMER DISPERSIONS EVONIK OPERATIONS GMBH (DE) 2020-11-25 EP disclosed
EP-3652151-B1 METHOD FOR PREPARING C-H ACIDIC (METH)ACRYLATES EVONIK OPERATIONS GMBH (DE) 2020-08-12 EP disclosed
EP-3655387-A1 CH-ACIDIC METHACRYLIC ESTERS FOR THE PREPARATION OF AQUEOUS POLYMER DISPERSIONS Evonik Operations GmbH (DE) 2020-05-27 EP disclosed
EP-3652151-A1 METHOD FOR PREPARING C-H ACIDIC (METH)ACRYLATES Evonik Operations GmbH (DE) 2020-05-20 EP disclosed
WO-2020016071-A1 METHOD FOR PREPARING C-H ACIDIC (METH)ACRYLATES EVONIK OPERATIONS GMBH (DE) 2020-01-23 WO disclosed
WO-2020016037-A1 CH-ACIDIC METHACRYLIC ESTERS FOR THE PREPARATION OF AQUEOUS POLYMER DISPERSIONS EVONIK OPERATIONS GMBH (DE) 2020-01-23 WO disclosed