Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.66 |
| ▸ | TP53 | P04637 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21623228 | 1.00 | MAPT (0.66) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL21623371 | 0.97 | MAPT (0.70) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL21623355 | 0.97 | MAPT (0.70) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL21623352 | 0.97 | MAPT (0.70) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL21623190 | 0.94 | MAPT (0.60) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL21624586 | 0.94 | MAPT (0.60) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL15076342 | 0.91 | MAPT (0.64) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL21623251 | 0.88 | MAPT (0.68) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL21623327 | 0.88 | MAPT (0.68) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL21623284 | 0.88 | MAPT (0.68) | MAPTTP53LMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016434-A1 | CYCLIC INHIBITORS OF HEPATITIS B VIRUS | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2020-01-23 | — | — | WO | disclosed |