SCHEMBL21625397

SCHEMBL21625397

CC(C)N1C(=O)C2CCCC3C(=O)NC(=O)C3CCCC2C1=O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.33
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PDE5A O76074 1/20 0.31
MAPK1 P28482 1/20 0.31
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21625400 0.98 PARP1 (0.33) PARP1NPC1RAB9ASMN1; SMN2PDE5A
SCHEMBL21625403 0.92 CYP19A1 (0.31)
SCHEMBL13684308 0.88 MAPK1 (0.37) NPC1RAB9ASMN1; SMN2PDE5AMAPK1
SCHEMBL21880291 0.86 PARP1 (0.31) PARP1
SCHEMBL12308315 0.84 SMN1; SMN2 (0.39) NPC1RAB9ASMN1; SMN2MAPK1PDE4A
SCHEMBL13532554 0.84 SMN1; SMN2 (0.39) NPC1RAB9ASMN1; SMN2MAPK1PDE4A
SCHEMBL24777091 0.81 HRH3 (0.32)
SCHEMBL21880678 0.77
SCHEMBL12428067 0.77 PARP1 (0.36) PARP1PDE4APDE4BPDE4CPDE4D
SCHEMBL6219549 0.77 PARP1 (0.36) PARP1PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10539832-B2 Photo alignment agent and liquid crystal display SAMSUNG DISPLAY CO., LTD. (KR) 2020-01-21 US disclosed