Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 15/20 | 0.44 |
| ▸ | TP53 | P04637 | 13/20 | 0.44 |
| ▸ | LMNA | P02545 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21626414 | 0.90 | MAPT (0.53) | MAPTTP53LMNAMEN1MAPK1 | |
| SCHEMBL21623054 | 0.85 | MAPT (0.47) | CYP1A2MAPTTP53LMNAMEN1 | |
| SCHEMBL21626518 | 0.83 | CYP1A2 (0.69) | CYP1A2MAPTTP53LMNAPIK3CD | |
| SCHEMBL21623120 | 0.82 | CYP1A2 (0.55) | CYP1A2MAPTTP53LMNAMEN1 | |
| SCHEMBL21623555 | 0.82 | CYP1A2 (0.43) | CYP1A2MAPTTP53LMNAMEN1 | |
| SCHEMBL21623376 | 0.81 | CYP1A2 (0.65) | CYP1A2MAPTTP53LMNARAB9A | |
| SCHEMBL21623241 | 0.81 | CYP1A2 (0.48) | CYP1A2MAPTTP53LMNACYP3A4 | |
| SCHEMBL21623238 | 0.81 | CYP1A2 (0.48) | CYP1A2MAPTTP53LMNACYP3A4 | |
| SCHEMBL21623378 | 0.81 | CYP1A2 (0.48) | CYP1A2MAPTTP53LMNACYP3A4 | |
| SCHEMBL21623574 | 0.80 | CYP1A2 (0.45) | CYP1A2MAPTTP53LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016427-A1 | INHIBITORS OF HEPATITIS B VIRUS | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2020-01-23 | — | — | WO | disclosed |
| WO-2020016434-A1 | CYCLIC INHIBITORS OF HEPATITIS B VIRUS | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2020-01-23 | — | — | WO | disclosed |
| EP-3597653-A1 | CYCLIC INHIBITORS OF HEPATITIS B VIRUS | IRBM S.P.A. (IT) | 2020-01-22 | — | — | EP | disclosed |
| EP-3597637-A1 | INHIBITORS OF HEPATITIS B VIRUS | IRBM S.P.A. (IT) | 2020-01-22 | — | — | EP | disclosed |