Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.46 |
| ▸ | FEN1 | P39748 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21623545 | 1.00 | TP53 (0.47) | TP53MAPTALOX5APFEN1LMNA | |
| SCHEMBL21623544 | 1.00 | TP53 (0.47) | TP53MAPTALOX5APFEN1LMNA | |
| SCHEMBL21626508 | 0.88 | CYP1A2 (0.46) | TP53MAPTALOX5APFEN1LMNA | |
| SCHEMBL21623077 | 0.84 | MAPT (0.56) | TP53MAPTALOX5APFEN1LMNA | |
| SCHEMBL21623359 | 0.84 | MAPT (0.56) | TP53MAPTALOX5APFEN1LMNA | |
| SCHEMBL21623078 | 0.84 | MAPT (0.56) | TP53MAPTALOX5APFEN1LMNA | |
| SCHEMBL21623379 | 0.82 | MAPT (0.68) | TP53MAPTALOX5APFEN1LMNA | |
| SCHEMBL21623151 | 0.82 | MAPT (0.68) | TP53MAPTALOX5APFEN1LMNA | |
| SCHEMBL21623153 | 0.82 | MAPT (0.68) | TP53MAPTALOX5APFEN1LMNA | |
| SCHEMBL15076479 | 0.80 | TP53 (0.61) | TP53MAPTLMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3597637-A1 | INHIBITORS OF HEPATITIS B VIRUS | IRBM S.P.A. (IT) | 2020-01-22 | — | — | EP | disclosed |