SCHEMBL2162890

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2164626	0.93	RAD51 (0.48)	TLR9TLR7NPM1ALKADORA2A
	SCHEMBL2162641	0.90	RAD51 (0.51)	TLR9TLR7NPM1ALKADORA2A
	SCHEMBL2163077	0.85	RAD51 (0.60)	TLR9TLR7ADORA2ARAD51ALDH1A1
	SCHEMBL12402969	0.85	RAD51 (0.47)	RAD51ALDH1A1SMN1; SMN2NPC1PKM
	SCHEMBL2164542	0.82	MAPT (0.55)	RAD51SMN1; SMN2MEN1KMT2AKDM4E
	SCHEMBL2162709	0.82	ADORA2A (0.56)	ADORA2AALDH1A1SMN1; SMN2NPC1HPGD
	SCHEMBL12403839	0.81	MAPT (0.42)	ADORA2ARAD51ALDH1A1SMN1; SMN2NPC1
	SCHEMBL2162700	0.81	RAD51 (0.50)	TLR9TLR7NPM1ALKRAD51
	SCHEMBL12402961	0.77	NPM1 (0.41)	NPM1ALKALDH1A1NPC1HPGD
	SCHEMBL2162678	0.77	TLR9 (0.40)	TLR9TLR7NPM1ALKALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.