SCHEMBL21633432

SCHEMBL21633432

CCOC(=O)C1=C(C)[N]N=C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
TSHR P16473 1/20 0.42
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA7 P43166 3/20 0.40
CA9 Q16790 3/20 0.40
CA14 Q9ULX7 3/20 0.40
KDM4E B2RXH2 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
HSP90AA1 P07900 1/20 0.40
LMNA P02545 2/20 0.39
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAOA P21397 1/20 0.39
ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21633299 0.73 CYP1A2 (0.43) CYP1A2TSHRCA12CA1CA2
SCHEMBL179565 0.68 CYP1A2 (0.50) CYP1A2TSHRKDM4EKMT2AMEN1
SCHEMBL16475880 0.68 CYP1A2 (0.46) CYP1A2TSHRCA12CA1CA2
SCHEMBL1019601 0.67 CYP1A2 (0.59) CYP1A2TSHRKDM4EKMT2AMEN1
SCHEMBL21843252 0.67 BRD4 (0.56) CYP1A2TSHRCA12CA1CA2
SCHEMBL489524 0.65 TSHR (0.52) CYP1A2TSHRCA12CA1CA2
SCHEMBL3010137 0.65 CYP1A2 (0.43) CYP1A2TSHRCA12CA1CA2
SCHEMBL4939167 0.65 CYP1A2 (0.43) CYP1A2TSHRCA12CA1CA2
SCHEMBL4045529 0.64 TSHR (0.61) TSHRCA12CA1CA2CA7
SCHEMBL12457581 0.64 CYP1A2 (0.46) CYP1A2TSHRCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828177-B1 PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2023-11-29 EP disclosed
EP-3828177-A1 PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2021-06-02 EP disclosed
WO-2020022412-A1 PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT 三井化学アグロ株式会社 2020-01-30 WO disclosed