Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18658265 | 0.78 | HSD17B10 (0.32) | — | |
| SCHEMBL24092186 | 0.72 | TSHR (0.32) | TSHR | |
| SCHEMBL22955373 | 0.72 | — | — | |
| SCHEMBL19185946 | 0.72 | — | — | |
| SCHEMBL21911226 | 0.70 | — | — | |
| SCHEMBL8297876 | 0.69 | — | — | |
| SCHEMBL24628754 | 0.69 | — | — | |
| SCHEMBL19636155 | 0.68 | — | — | |
| SCHEMBL23678936 | 0.68 | — | — | |
| SCHEMBL3638444 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016443-A1 | DIFLUOROMETHYL-PHENYL TRIAZOLES AS GABA RECEPTOR MODULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-01-23 | — | — | WO | disclosed |