SCHEMBL21636007

SCHEMBL21636007

O=c1c2ccccc2c2cc3ncccc3cc2n1-c1ccc2c3ccccc3c3ccccc3c2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2C9 P11712 1/20 0.43
GAA P10253 4/20 0.38
POLB P06746 3/20 0.38
MAPT P10636 3/20 0.38
ALDH1A1 P00352 2/20 0.38
LOXL3 P58215 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
KDM4E B2RXH2 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPK1 P28482 2/20 0.37
HPGD P15428 3/20 0.37
CYP3A4 P08684 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
PSMD14 O00487 1/20 0.37
TP53 P04637 1/20 0.37
MMP2 P08253 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14933482 0.84 MEN1 (0.41) CYP2C19CYP2C9GAAMAPTALDH1A1
SCHEMBL20227637 0.74 MAPK1 (0.52) CYP1A2CYP2C19CYP2C9POLBMAPT
SCHEMBL20227625 0.74 MAPK1 (0.52) CYP1A2CYP2C19CYP2C9POLBMAPT
SCHEMBL21636055 0.74 MAPK1 (0.52) CYP1A2CYP2C19CYP2C9POLBMAPT
SCHEMBL21636019 0.72 IDO1 (0.37) CYP1A2CYP2C19CYP2C9MAPTALDH1A1
SCHEMBL20227671 0.72 ERN1 (0.41) CYP2C19CYP2C9POLBMAPTALDH1A1
SCHEMBL21636068 0.72 MAPK1 (0.46) CYP1A2CYP2C19CYP2C9POLBMAPT
SCHEMBL16484366 0.69 MAPT (0.55) GAAPOLBMAPTALDH1A1KDM4E
SCHEMBL21636086 0.69 MAPK1 (0.46) CYP1A2CYP2C19CYP2C9GAAPOLB
SCHEMBL21636026 0.69 MAPK1 (0.46) CYP1A2CYP2C19CYP2C9GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3823958-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-08-23 EP disclosed
WO-2020016264-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-01-23 WO disclosed