SCHEMBL21636087

SCHEMBL21636087

Brc1ccc2c(c1)c1ccccc1c1ccc(Br)cc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
RXFP1 Q9HBX9 1/20 0.52
CYP2A6 P11509 2/20 0.48
AHR P35869 1/20 0.42
HPRT1 P00492 3/20 0.41
CDK2 P24941 3/20 0.41
PRKD3 O94806 2/20 0.41
MAP4K4 O95819 2/20 0.41
CSF1R P07333 2/20 0.41
FLT3 P36888 2/20 0.41
CLK2 P49760 2/20 0.41
MAP4K2 Q12851 2/20 0.41
DYRK1A Q13627 2/20 0.41
NTRK3 Q16288 2/20 0.41
AURKB Q96GD4 2/20 0.41
CLK4 Q9HAZ1 2/20 0.41
CAMK2B Q13554 2/20 0.41
CAMK2G Q13555 2/20 0.41
DCLK1 O15075 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29476069 1.00 MEN1 (0.52) MEN1KMT2ARXFP1CYP2A6AHR
SCHEMBL21764548 1.00 MEN1 (0.52) MEN1KMT2ARXFP1CYP2A6AHR
Triphenylene SCHEMBL1923284 1.00 MEN1 (0.52) MEN1KMT2ARXFP1CYP2A6AHR
SCHEMBL12580921 1.00 MEN1 (0.52) MEN1KMT2ARXFP1CYP2A6AHR
SCHEMBL16076434 1.00 MEN1 (0.52) MEN1KMT2ARXFP1CYP2A6AHR
SCHEMBL312606 1.00 MEN1 (0.52) MEN1KMT2ARXFP1CYP2A6AHR
SCHEMBL29656894 1.00 MEN1 (0.52) MEN1KMT2ARXFP1CYP2A6AHR
SCHEMBL21176157 0.92 MEN1 (0.47) MEN1KMT2ARXFP1CYP2A6AHR
SCHEMBL16158369 0.91 CYP2A6 (0.47) MEN1KMT2ARXFP1CYP2A6AHR
SCHEMBL19396754 0.90 MEN1 (0.46) MEN1KMT2ARXFP1CYP2A6AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3823958-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-08-23 EP disclosed
WO-2020016264-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-01-23 WO disclosed