Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 13/20 | 0.64 |
| ▸ | MAPT | P10636 | 12/20 | 0.64 |
| ▸ | LMNA | P02545 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | STK25 | O00506 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23790478 | 0.92 | MAPT (0.54) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL17085002 | 0.88 | MAPT (0.81) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL21626515 | 0.85 | TP53 (0.67) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL15076594 | 0.85 | MAPT (0.73) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL15076403 | 0.84 | MAPT (0.74) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL21623255 | 0.83 | MAPT (0.73) | TP53MAPTLMNAKMT2APOLB | |
| SCHEMBL15277009 | 0.81 | MAPT (0.70) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL21623202 | 0.81 | MAPT (0.60) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL15076422 | 0.80 | MAPT (0.71) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL21623313 | 0.80 | CYP1A2 (0.55) | TP53MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016434-A1 | CYCLIC INHIBITORS OF HEPATITIS B VIRUS | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2020-01-23 | — | — | WO | disclosed |