Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 15/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12196108 | 0.85 | EPHX1 (1.00) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL3418374 | 0.81 | EPHX1 (0.93) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL30832056 | 0.81 | EPHX1 (0.45) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL12260711 | 0.78 | EPHX1 (0.66) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL14100144 | 0.78 | EPHX1 (0.68) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL12260729 | 0.77 | EPHX1 (0.47) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL7776480 | 0.76 | EPHX1 (0.75) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL5109892 | 0.72 | KMT2A (0.50) | EPHX1 | |
| SCHEMBL14365670 | 0.72 | MAPK1 (0.48) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL17354481 | 0.72 | MAPK1 (0.48) | EPHX1KDM4EALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210187111-A1 | COMPOSITIONS AND METHODS FOR DISRUPTING A MACROPHAGE NETWORK | SCRIPPS HEALTH (US) | 2021-06-24 | — | — | US | disclosed |
| WO-2020018434-A1 | COMPOSITIONS AND METHODS FOR DISRUPTING A MACROPHAGE NETWORK | SCRIPPS HEALTH (US) | 2020-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210187111-A1 | COMPOSITIONS AND METHODS FOR DISRUPTING A MACROPHAGE NETWORK | MSR1, CD68, CD209 | EPHX1 766/4885KDM4E 3715/4885ALDH1A1 4611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.