Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.43 |
| ▸ | GPER1 | Q99527 | 3/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21638629 | 0.95 | BRD4 (0.42) | BRD4GPER1KHKPIK3CAIDH1 | |
| SCHEMBL16721676 | 0.87 | BRD4 (0.49) | BRD4GPER1PIK3CAIDH1NAMPT | |
| SCHEMBL16721882 | 0.86 | BRD4 (0.54) | BRD4GPER1 | |
| SCHEMBL21638521 | 0.85 | BRD4 (0.44) | BRD4GPER1IDH1NAMPT | |
| SCHEMBL21638620 | 0.85 | BRD4 (0.46) | BRD4GPER1NAMPT | |
| SCHEMBL16722015 | 0.85 | BRD4 (0.57) | BRD4GPER1PIK3CAIDH1NAMPT | |
| SCHEMBL16722013 | 0.85 | BRD4 (0.57) | BRD4GPER1PIK3CAIDH1NAMPT | |
| SCHEMBL21638615 | 0.85 | BRD4 (0.55) | BRD4GPER1KHKFGFR3 | |
| SCHEMBL21638456 | 0.85 | BRD4 (0.49) | BRD4GPER1PIK3CAIDH1NAMPT | |
| SCHEMBL21638625 | 0.84 | BRD4 (0.45) | BRD4GPER1PIK3CAIDH1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |