SCHEMBL216412

SCHEMBL216412

CC(C)(C)OC(=O)N1CC(O)C1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.56
CHRM2 P08172 1/20 0.52
CHRM1 P11229 1/20 0.52
CHRM3 P20309 1/20 0.52
USP2 O75604 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HPGD P15428 1/20 0.46
RECQL P46063 1/20 0.44
EPHX1 P07099 1/20 0.44
DDB1 Q16531 1/20 0.42
CRBN Q96SW2 1/20 0.42
NAMPT P43490 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
EPHX2 P34913 1/20 0.41
RORC P51449 1/20 0.41
GPR119 Q8TDV5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28493671 0.92 NR1H2 (0.50) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL16903484 0.92 CHRM2 (0.53) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL22413119 0.92 NR1H2 (0.57) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL22413118 0.92 NR1H2 (0.57) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL16985478 0.92 NR1H2 (0.57) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL25078967 0.92 CHRM2 (0.53) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL20775206 0.92 NR1H2 (0.49) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL21828168 0.92 USP2 (0.52) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL31433037 0.92 NR1H2 (0.57) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL29105865 0.92 NR1H2 (0.57) NR1H2CHRM2CHRM1CHRM3USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3513 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504544-A Preparation method of N-Boc-3-amino azetidine 宿迁晨阳医药科技有限公司 2025-02-25 CN claimed
CN-119144118-A High-transparency high-strength high-toughness epoxy resin composite material and preparation method thereof 索罗曼(常州)合金新材料有限公司 2024-12-17 CN claimed
CN-118530153-A Preparation method of 1-Boc-3-azetidinone 上海津力药业股份有限公司 2024-08-23 CN claimed
CN-115974864-A Synthetic method of 2- (3-azetidinyl) thiazole salt 苏州汉德创宏生化科技有限公司 2023-04-18 CN claimed
EP-4143179-A1 AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS Idorsia Pharmaceuticals Ltd (CH) 2023-03-08 EP claimed
CN-114874121-A Method for preparing material containing monothiocarbonate group and product 浙江大学 2022-08-09 CN claimed
CN-113582901-A Method for preparing aldehyde or ketone by oxidizing alcohol through oxidation reaction 浙江瑞博制药有限公司 2021-11-02 CN claimed
CN-110683978-A Preparation method of 3-nitrile methylene azetidine-1-tert-butyl carbonate 西安医学院 2020-01-14 CN claimed
CN-109053524-A A kind of preparation method of N-Boc-3- hydroxy azetidine 山东谛爱生物技术有限公司 2018-12-21 CN claimed
CN-106831523-A The preparation method of 3 hydroxy azetidine hydrochlorides and the hydroxy azetidines of N Boc 3 四川同晟生物医药有限公司 2017-06-13 CN claimed
EP-3114126-A1 1,2-DIHYDRO-3H-PYRROLO[1,2-C]IMIDAZOL-3-ONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS Actelion Pharmaceuticals Ltd (CH) 2017-01-11 EP claimed
CN-106008303-A Preparation method of 1-Boc-3-hydroxyl azetidine medical intermediate 苏州艾缇克药物化学有限公司 2016-10-12 CN claimed
CN-105622469-A Preparation method of alkyl sulfonyl chloride containing nitrogen and fluorine HANDE SCIENCES CO LTD 2016-06-01 CN claimed
WO-2015132228-A1 1,2-DIHYDRO-3H-PYRROLO[1,2-C]IMIDAZOL-3-ONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS ACTELION PHARMACEUTICALS LTD (CH) 2015-09-11 WO claimed
CN-102432514-A Synthesis method of 1-tert-butyloxycarbonyl-3-fluoroazetidine LANZHOU BOSHI BIOCHEMICAL TECHNOLOGY CO LTD 2012-05-02 CN claimed
CN-102276511-A Synthetic method for 1-tert-butyloxycarbonyl-3-iodo-azetidine 2011-12-14 CN claimed
CN-102212026-A Preparation method for 1-tertbutyloxycarbonyl-3-iodoazetidine SHANGHAI ELITTES ORGANICS CO LTD 2011-10-12 CN claimed
EP-2300470-A2 IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS GABA-A RECEPTOR MODULATORS Sepracor Inc. (US) 2011-03-30 EP claimed
CN-101676263-A Method for synthesizing N-tert-butoxycarbonyl group-3-hydroxy azetidine TIANJIN APPTEC CO LTD 2010-03-24 CN claimed
WO-2009143156-A2 IMIDAZO[1,2-a]PYRIDINE COMPOUNDS SEPRACOR INC. (US) 2009-11-26 WO claimed