Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.67 |
| ▸ | HSP90AB1 | P08238 | 8/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644573 | 0.87 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1NPSR1ALDH1A1 | |
| SCHEMBL21644530 | 0.85 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1NPSR1 | |
| SCHEMBL21644647 | 0.84 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1ALDH1A1TP53 | |
| SCHEMBL21644548 | 0.82 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1 | |
| SCHEMBL487667 | 0.82 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL21644710 | 0.82 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1 | |
| SCHEMBL30779632 | 0.82 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1 | |
| SCHEMBL21644542 | 0.78 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL20509059 | 0.78 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1NPSR1SMN1; SMN2TP53 | |
| SCHEMBL21644708 | 0.77 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111164074-B | Heat shock protein 90 inhibitors | 台北医学大学 | 2024-02-02 | — | — | CN | disclosed |
| US-11479528-B2 | Heat shock protein 90 inhibitors | TAIPEI MEDICAL UNIVERSITY (TW) | 2022-10-25 | — | — | US | disclosed |
| CN-111164074-A | Heat shock protein 90 inhibitor | 台北医学大学 | 2020-05-15 | — | — | CN | disclosed |
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | HSP90AA1 3/4885HSP90AB1 1/4885NPSR1 4015/4885 |
| US-11479528-B2 | Heat shock protein 90 inhibitors | HSP90AB1, HSP90AB2P, HSP90AA1 | HSP90AA1 3/4885HSP90AB1 1/4885NPSR1 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.