Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27758866 | 0.80 | SLC29A1 (0.44) | BRD4POLBSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4265964 | 0.76 | CYP1A2 (0.60) | POLBSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL179780 | 0.75 | KMT2A (0.52) | BRD4POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL28221636 | 0.73 | BRD4 (0.42) | BRD4POLBSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10147178 | 0.73 | BRD4 (0.42) | BRD4POLBSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10147187 | 0.73 | SMN1; SMN2 (0.53) | BRD4POLBSMN1; SMN2KCNH2CYP2D6 | |
| SCHEMBL28957334 | 0.73 | POLB (0.46) | POLBSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL18787552 | 0.73 | BRD4 (0.34) | BRD4POLBSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2638232 | 0.72 | KCNH2 (0.42) | BRD4POLBSMN1; SMN2ALDH1A1KMT2A | |
| Bromide SCHEMBL10795216 | 0.72 | TLR8 (0.50) | BRD4POLBSMN1; SMN2KCNH2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028616-A1 | METHODS FOR MANUFACTURING RECOMBINANT PROTEIN COMPRISING A DISULFIDE BOND | LONZA LTD (CH) | 2020-02-06 | — | — | WO | disclosed |